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Delivering world-class research

Our research addresses four big, neglected problems in healthcare: antibiotic resistance, overdiagnosis, waste in research, and neglected non-drug treatment. Our focus in these areas assists health systems to provide care that is patient-centred and informed by evidence, and enables patients to make decisions that are congruent with their values, preferences and circumstances.

Antibiotic resistance

currently leads to 30,000 avoidable deaths per year in Europe and the USA, threatens elective surgery, and foreshadows a resurgence of the bacterial diseases of the 19th century.

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Overdiagnosis

has led to a massive increase in the apparent prevalence of many diseases through definition change and overdetection, and rising healthcare costs.

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Neglected non-drug treatments

are often as effective and as safe, or safer than their pharmaceutical cousins but are poorly described, poorly “marketed”, and therefore little used.

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Waste in medical research

is estimated to cost over $100 billion per  year from avoidable design flaws, non-publication and poor reporting, resulting in >85% avoidable waste.

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Long Covid

Currently, there is no specific treatment for Long COVID, and strong evidence on what works best is still lacking.

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Cochrane Acute Respiratory Infections (ARI) Group

Cochrane is an international, not-for-profit collaboration of 26 Review Groups, 12 Thematic Groups, and 5 Evidence Synthesis Units producing comprehensive systematic reviews on a broad range of health topics.

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Cardiovascular Disease

Solving the long-standing evidence-practice gap associated with cardiac rehabilitation and secondary prevention of coronary heart disease

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Research centres

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